8:20 Welcome Address And Chairperson’s Recap Of Day One

8:30 Compound Management Case Study: The US National Institute Of Health Molecular Libraries Small Molecule Repository

• Presenting the NIH Molecular Libraries Program and the decision to outsource CM
• Collaborating with BioFocus DPI to identify, select, and acquire the MLSMR collection
• Displaying NIH’s choices for sample QC, processing, storage, and plating
• Managing the many-way relationship between NIH, BioFocus DPI, and HTS screening centers
• Coordinating data between MLSMR and the screening centers, and making it publicly available

Jamie Driscoll
Chief of Research Services, Division of Neuroscience and Basic Behavioral Science
National Institute of Mental Health

9:15 Automation From Compound Storage To High Throughput Screening

• Maintain The Compound Library For HTS With both Sample-based And Plate-based Storages
• Supply HTS With “Just-In-Time” Assay Ready Plates On Demand
• Screen Up To 100000 Compounds A Day Per Project
• Provide assay-ready Compounds Within 48 Hours For HTS Follow Up

Dalin Nie, PhD
Head Of Compound Management
AstraZeneca

10:45 Maximizing Your Investment: Lifecycle Management Of Automation, Obsolescence And System Development

• Discussing the changing economic climate and automation investment strategies
• Describing the approaches to maximize current investments and introduce flexibility
• Displaying approaches to determining system obsolescence and strategies to minimize exposure and risk
• Understanding system developments to meet business need

Cris Avram
Automation Specialist, Sample Management Technologies
GlaxoSmithKline

11:30 Enabling LO/SAR Through The Evolution Of Flexible Sample Management Technologies

• Discussing the drivers for flexibility and diversity in Lead Optimization and SAR
• Presenting approaches for accelerating LO/SAR through "Express IP", flexibility scheduling and iterative panel approaches
• Present approaches for addressing the need for high content data, critical to late stage discovery in Pre-Candidate Profiling
• Discussing and present case studies demonstrating the impact that acoustic dispensing has had on the LO/SAR compound handling
• Displaying the drivers and processes for monitoring sample quality during LO/SAR

Brenda Li
Senior Scientist, Sample Management Technologies
GlaxoSmithKline

1:15 Implementation Of A High Throughput Assay Ready Plate (HARP) System At Novartis Utilizing Acoustic Droplet Ejection

• Utilizing two integrated Labcyte Echo dispensers with backfill capabilities using a Thermo Combi nl bulk dispenser
• Exploring and understanding online compound stores containing 1.2 million compound solutions
• Displaying system capabilities of dispensing up to 400K samples per day in nanoliter volumes from 1536 source plates
• Presenting in addition to a single point, formats include that 2,4 and 8 dilution series plates in both 384 and 1536 destinations
• Discussing Biological Acceptance Testing (BAT) and plate storage experimental data

Scott Bowes
Scientist II, CPC, Lead Finding Platform
Novartis Institute of Biomedical Research

2:00 TECHNICAL SESSION: Increasing HTS Productivity With Automated Assay Plate Creation

• Maximizing The Unique Capabilities Of Echo Liquid Handlers For Automated Assay Plate Creation
• Creating And Modifying Protocols On-The-Fly Without Special Programming Expertise
• Automating Protocol Creation For Plate Replication, Doseresponse Curve Set-Up, Cherry Picking
• Customizing Data Reporting For LIMS Compatibility

Jean Shieh
Product Manager
Labcyte Inc.

2:45 Improving Data Quality For Lead Optimization Compounds Through Iterative Evaluation And Then Implementation Of New Processes

• Examining challenges associated with handling potent, "sticky", and hazardous compounds
• Evaluating rigorous quality control identified biologically active chemicals from the plastics used in common compound handling procedures
• Discussing improvement in data interpretation have been facilitated by the adoption of nephelometry measurement in Compound Management.

Sandra Matson
Research Scientist
Bristol-Myers Squibb Company

4:00 Titian Software’s Annual 2009 User Group Meeting

This will include presentations from existing Titian customers and staff members who will participate in roundtable discussion groups focusing on key topics. Also, network and relax at the Titian User Group Meeting customer dinner at the end of the meeting’s first day. Learn from and exchange knowledge amongst your peers.

This is a privately held, invitation only meeting.